MICROBIOLOGICAL MONITORING OF CLEANROOMS IN THE PRODUCTION OF STERILE PRODUCTS

The study presents the results of microbiological assessment of cleanrooms during the industrial production of foot-and-mouth disease vaccine under aseptic processing conditions. The investigations were conducted in Grade A and B areas during 2024–2025. More than 1,800 samples of air, equipment surfaces, and personnel gowning were analyzed. No microbial contamination was detected in air or on production surfaces. In 1.9% of samples taken from personnel garments and gloves, single microorganisms were identified within acceptable regulatory limits. The obtained data indicate the stability of aseptic conditions and the controlled state of the production environment.

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