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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">biob</journal-id><journal-title-group><journal-title xml:lang="ru">Биобезопасность и Биотехнология</journal-title><trans-title-group xml:lang="en"><trans-title>Biosafety and Biotechnology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2707-7241</issn><issn pub-type="epub">2957-5702</issn><publisher><publisher-name>Научно-исследовательский институт проблем биологической безопасности</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">biob-207</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МЕДИЦИНСКАЯ И ВЕТЕРИНАРНАЯ БИОТЕХНОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>MEDICAL AND VETERINARY BIOTECHNOLOGY</subject></subj-group></article-categories><title-group><article-title></article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives/><email xlink:type="simple">bauken_68@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">казахский национальный аграрный исследовательский университет<country>Казахстан</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>17</day><month>04</month><year>2026</year></pub-date><volume>0</volume><issue>24</issue><elocation-id>207</elocation-id><permissions><copyright-statement>Copyright &amp;#x00A9; Otarbayev B., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Otarbayev B.</copyright-holder><copyright-holder xml:lang="en">Otarbayev B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.biosafety.kz/jour/article/view/207">https://journal.biosafety.kz/jour/article/view/207</self-uri></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Әдебиеттер</mixed-citation><mixed-citation xml:lang="en">References (Latin transliteration)</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Jain S., Bloom B.R., Hondalus M.K. 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