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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">biob</journal-id><journal-title-group><journal-title xml:lang="ru">Биобезопасность и Биотехнология</journal-title><trans-title-group xml:lang="en"><trans-title>Biosafety and Biotechnology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2707-7241</issn><issn pub-type="epub">2957-5702</issn><publisher><publisher-name>Научно-исследовательский институт проблем биологической безопасности</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">biob-171</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МЕДИЦИНСКАЯ И ВЕТЕРИНАРНАЯ БИОТЕХНОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>MEDICAL AND VETERINARY BIOTECHNOLOGY</subject></subj-group></article-categories><title-group><article-title></article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0008-6139-5524</contrib-id><name-alternatives/><email xlink:type="simple">o.orazbek@biosafety.kz</email></contrib></contrib-group><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>26</day><month>09</month><year>2025</year></pub-date><volume>1</volume><issue>22</issue><elocation-id>171</elocation-id><permissions><copyright-statement>Copyright &amp;#x00A9; Серикбайов О.Н., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Серикбайов О.Н.</copyright-holder><copyright-holder xml:lang="en">Серикбайов О.Н.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.biosafety.kz/jour/article/view/171">https://journal.biosafety.kz/jour/article/view/171</self-uri></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">ҚОЛДАНЫЛҒАН ӘДЕБИЕТТЕР</mixed-citation><mixed-citation xml:lang="en">REFERENCES</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Мека-Меченко В.Г., Некрасова Л.Е., Мека-Меченко Т.В., Лухнова Л.Ю., Куница Т.Н., Избанова У.А., Бегимбаева Э.Ж. Пастереллез животных в Республике Казахстан // Вестник КазНУ. – 2014. - № 40. Б. 156-159.</mixed-citation><mixed-citation xml:lang="en">Meka-Mechenko V.G., Nekrasova L.E., Meka-Mechenko T.V., Lukhnova L.Yu., Kunitsa T.N., Izbanova U.A., Begimbaeva E.Zh. Pasteurellosis of animals in the Republic of Kazakhstan // Vestnik KazNU. - 2014. No. 40. p. 156-159.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Сайдулдин Т. Індеттану және жануарлардың жұқпалы аурулары Алматы – 2009. – 206 б.</mixed-citation><mixed-citation xml:lang="en">Saiduldin T. Epidemiology and infectious diseases of animals. - Almaty, 2009. 206 p.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Намет А.М. Иммунопрофилактика пастереллеза лошадей: автореф Алматы – 2006. – 3 б.</mixed-citation><mixed-citation xml:lang="en">Namet A.M. Immunoprophylaxis of pasteurellosis in horses: autoref. dr. Vet. science - Almaty, 2006. 3 p.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Кожаев А.Н. Поливалентная вакцина против пастереллеза сельскохозяйственных животных // Алматы – 2008. – 3 б.</mixed-citation><mixed-citation xml:lang="en">Kojaev A.N. Polyvalent vaccine against pasteurellosis of farm animals. - Almaty, 2008. 3p.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Борисенкова А.Н. Рекомендации по диагностике, профилактике и мерам борьбы с пастереллезом птиц: технологические процессы // Госагропром СССР. – 1986. – 25 б.</mixed-citation><mixed-citation xml:lang="en">Borisenkova A.N. Recommendations for diagnosis, prevention and measures to combat pasteurellosis in birds: technological process // Gosagroprom of the USSR. VNIVIP. - L., 1986. 25 p.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Rimler, R. B. &amp; Rhoades, K. R. Pasteurella multocida. In Pasteurella and Pasteurellosis // Academic Press. London. – Б. 37-73</mixed-citation><mixed-citation xml:lang="en">Rimler, R. B. &amp; Rhoades, K. R. Pasteurella multocida. In Pasteurella and Pasteurellosis // Academic Press. - London.. pp. 37-73</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Осидзе Д.Ф. Инфекционные болезни животных // Москва, – 1987. – 188 с.</mixed-citation><mixed-citation xml:lang="en">Osidze D.F. Infectious diseases of animals. - Moscow, 1987, 188 p.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Гибель сайгаков в Костанайской, Актюбинской и Акмолинской областях [Электрон.ресурс]https://www.cms.int/saiga/sites/default/files/document/1.%20TW%2026.10_Abdrahmanov_%20Overview%20of%20the%202015%20saiga%20mass%20mortality%20event%20in%20Kazakhstan.pdf</mixed-citation><mixed-citation xml:lang="en">Death of saigakov in Kostanay, Aktyubin and Akmola regions [Electronic resource]. https://www.cms.int/saiga/sites/default/files/document/1.%20TW%2026.10_Abdrahmanov_%20Overview%20of%20the%202015%20saiga%20mass%20mortality%20event%20in%20Kazakhstan.pdf</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">З.А. Латыпова, А.М. Намет, Б.Ж. Исакулова, З.К. Буйенбаева, Р.А. Керимбаева</mixed-citation><mixed-citation xml:lang="en">Z.A. Latypova, A.M. Namet, B.J. Isakulova, Z.K. Buyenbaeva, R.A. Kerimbaeva</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Зонирование территории республики казахстан по степени распространения заболевания пастереллёзом среди крупного рогатого скота // Микробиология және вирусология. – 2022 г. – Б. 55-63 DOI:10.53729/MV-AS.2022.03.04.</mixed-citation><mixed-citation xml:lang="en">Zoning of the territory of the republic of Kazakhstan according to the degree of prevalence of pasteurellosis among large cattle // Microbiology and virology. - 2022 str. 55-63 DOI:10.53729/MV-AS.2022.03.04.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Евтыхова Е.Б., Мукантаев К.Н., Турсунов К., Сытник И.И., Карибаев Т.Б., Хасенов Б.Б., Шустов А.Б. Метод выделения ДНК и тест-система ПЦР в реальном времени для диагностики лейкоза крупного рогатого скота // Биотехнология. Теория и практика. – 2012. -№ 2. – Б. 78–84.</mixed-citation><mixed-citation xml:lang="en">Evtykhova E.B., Mukantaev K.N., Tursunov K., Sytnik I.I., Karibaev T.B., Khasenov B.B., Shustov A.B. The method of DNA extraction and test system PCR in real time</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Далбаев Н.К., Кайсенов Д.Н., Султанкулова К.Т., Тайлакова Э.Т., Червякова О.В, Алиева А.Б., Абсатова Ж.С., Баракбаев К.Б. Получение генетически аттенуированного</mixed-citation><mixed-citation xml:lang="en">for diagnosis of leukemia of large horned cattle // Biotechnology. Theory and practice. - 2012. No. 2. p. 78–84.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">АroА мутантного штамма Pasteurell multocida.//Международный журнал прикладных</mixed-citation><mixed-citation xml:lang="en">Getting genetically attenuated AroAmutantnogoshtammaPasteurell multocida.Dalbaev N.K., Kaysenov D.N., Sultankulova K.T., Tailakova E.T., Chervyakova O.V, Alieva A.B., AbsatovaZh. S., Barakbaev K.B. International Journal of Applied and Fundamental Studies. No. 3, 2020</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">и фундаментальных исследований. – 2020. – № 3.</mixed-citation><mixed-citation xml:lang="en">Pallab Chaudhuri, V.P.Singh, A Thamizharasan, Jonathan Lalsiamthara Pasteurella multocida P52 aroA mutant conferred protection to rabbits and mice against haemorrhagic septicemia Division of Bacteriology &amp; Mycology. - Indian Veterinary Research Institute, Izatnagar, - India</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Pallab Chaudhuri, V.P.Singh, A Thamizharasan, Jonathan Lalsiamthara. Pasteurella multocida P52 aroA mutant conferred protection to rabbits and mice against haemorrhagic septicaemia // DHR International Journal of Biomedical and Life Sciences. – 2012. – Б 2278-8301.</mixed-citation><mixed-citation xml:lang="en">Saleem L., Munir R., Ferrari G., Afzal M., Chaudhary F.R. Efficacy and cross protection of live intranasal aerosol hemorrhagic septicemia vaccine in buffalo calves. International Journal of Current Microbiology and Applied Sciences. 2014. Vol. 3. - R. 300–307.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Saleem L., Munir R., Ferrari G., Afzal M., Chaudhary F.R. Efficacy and cross protection of live intranasal aerosol hemorrhagic septicemia vaccine in buffalo calves. // International Journal of CurrentMicrobiology and Applied Sciences. – 2014. - № 3. – Б. 300–307.</mixed-citation><mixed-citation xml:lang="en">Mohammad Tabatabaei, G. R. Moazzeni Jula, A. R. Jabbari and M. Esmailzadeh. Vaccine efficacy in cattle against hemorrhagic septicemia with live attenuated aro/A mutant of Pasteurella multocida B:2 strain. Journal of Cell and Animal Biology  2007 - 1 (4), pp. 062-065, November,</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Mohammad Tabatabaei, G. R. Moazzeni Jula, A. R. Jabbari and M. Esmailzadeh. Vaccine efficacy in cattle against hemorrhagic septicemia with live attenuated aroA mutant of Pasteurella multocida B:2 strain. // Journal of Cell and Animal Biology – 2007. - № (4). – Б. 062-065.</mixed-citation><mixed-citation xml:lang="en">Verta N.D. P.multocida B:2 in haemorrhagic septicemia outbreak in pigs in India // Vet.Res. - 1988. - Vol. 123. - P. 63-69.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Verta N.D. P.multocida B:2 in haemorragic septicemia outbreak in pigs in India // Vet.Res. – 1988. - № 123. – Б. 63-69.</mixed-citation><mixed-citation xml:lang="en">Dwived P.N., Sodhi S.S. Isolation and serotyping of P.multocida from Punjab // Indian J.anamsc. - 1989. - Vol. 59. - P. 545-547.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Dwived P.N., Sodhi S.S. Isolation and serotyping of P.multocida from Punjab // Indian J.anamsc. – 1989. -№59. – Б. 545-547.</mixed-citation><mixed-citation xml:lang="en">Carter G.R. Studies on P. multocida. 2. Identification of antigenic characteristics and colonial variants // Amer.J.Vet.Res. - 1957. - Vol. 18.- P. 210-213.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Carter G.R. Identification of antigenic characteristics and colonial variants // Vet.Res. – 1957. - №18. – Б. 210-213.</mixed-citation><mixed-citation xml:lang="en">Hummel P.H. Isolation of P.multocida Carter type E in Tanzania // Vet.Rec. - 1970. - Vol. 86. - P. 42-43.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Hummel P.H. Isolation of P.multocida Carter type E in Tanzania // Vet.Rec. – 1970. - № 86. – Б. 42-43.</mixed-citation><mixed-citation xml:lang="en">Voigts A., Ngaisiue G., HentonM.M., Hubschle O.J.B. Hemorrhagic septicemia due to Pasteurella multocida type B 2 in Namibia // Trop anim - health -prod. - 1997. - Vol. 29 (4). - P. 247-248.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Voigts A., Ngaisiue G., HentonM.M., Hubschle O.J.B. Hemorrhagic septicemia due to Pasteurella multocida type В 2 in Namibia // Trop anim health prod. – 1997. - № 29 (4). – Б. 247-248.</mixed-citation><mixed-citation xml:lang="en">Hill B.D., Johnson RB. P.multocida septicemia in two calves // Aust.Vet.J. - 1992. - Vol. 69. - P. 197-198.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Hill B.D., Jonhson R.B. P.multocida septicemia in two calves // Aust.Vet.J. – 1992. - № 69. – Б. 197-198.</mixed-citation><mixed-citation xml:lang="en">Blackball P.J., Fegan N., Chew G.T.I., Hampson D.J. Population structure and diversity of avian isolates of Pasteurella multocida from Australia // Microbiol. Reading. - 1998. - Vol. 144. - P. 279-289.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Blackball P.J., Fegan N., Chew G.T.I., Hampson D.J. Population structure and diversity of avian isolates of Pasteurella multocida from Australia // Microbiol. Reading. – 1998. - № 144. – Б. 279-289.</mixed-citation><mixed-citation xml:lang="en">Hoiseth SK, Stocker BA. Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines // Nature. - 1981. - P. 238-239.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Hoiseth S.K., Stocker B.A. Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines // Nature. – 1981. – Б. 238-239.</mixed-citation><mixed-citation xml:lang="en">Scott PC, Markham JF, Whithear KG. Safety and efficacy of two live Pasteurella multocida aroA mutant vaccines in chickens // Avian Dis. - 1999. - Vol. 43. - R. 83-88.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Scott P.C., Markham J.F., Whithear K.G. Safety and efficacy of two live Pasteurella multocida aroA mutant vaccines in chickens // Avian Dis. – 1999. - № 43. – Б. 83-88.</mixed-citation><mixed-citation xml:lang="en">Scott P.C., Markham J.F., Whithear K.G. Safety and efficacy of two live Pasteurella multocida aroA mutant vaccines in chickens // Avian Dis. – 1999. - № 43. – Б. 83-88.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
