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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">biob</journal-id><journal-title-group><journal-title xml:lang="ru">Биобезопасность и Биотехнология</journal-title><trans-title-group xml:lang="en"><trans-title>Biosafety and Biotechnology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2707-7241</issn><issn pub-type="epub">2957-5702</issn><publisher><publisher-name>Научно-исследовательский институт проблем биологической безопасности</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.58318/2957-5702-2024-17-46-56</article-id><article-id custom-type="elpub" pub-id-type="custom">biob-123</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>О СЛУЧАЯХ ВЫЯВЛЕНИЯ ТУБЕРКУЛЕЗА КРУПНОГО РОГАТОГО СКОТА В КАРАГАНДИНСКОЙ И УЛЫТАУСКОЙ ОБЛАСТЯХ</article-title><trans-title-group xml:lang="en"><trans-title>CASES OF DETECTION OF BOVINE TUBERCULOSIS IN KARAGANDA AND ULYTAU REGIONS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2722-2020</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Борсынбаева</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Borsynbayeva</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Борсынбаева Асия Маденовна, PhD, ведущий научный сотрудник</p></bio><email xlink:type="simple">asiajan@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3069-0861</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дюсенов</surname><given-names>С. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Dyusenov</surname><given-names>S. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дюсенов Сайран Мырзаханович, кандидат ветеринарных наук, заведующий филиала "Карагандинского НИВС"</p></bio><email xlink:type="simple">kar_nivs@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0008-6627-8415</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Оразбеков</surname><given-names>Е. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Orazbekov</surname><given-names>E. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Оразбеков Ералы Бакенович, кандидат ветеринарных наук, старший научный сотрудник</p></bio><email xlink:type="simple">eraly.orazbekov58@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2722-2020</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Акжунусова</surname><given-names>И. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Akzhunusova</surname><given-names>I. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Акжунусова Индира Куанышбековна, магистр биологических наук, научный сотрудник</p></bio><email xlink:type="simple">akzhunusova76@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4252-7033</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сейтжанова</surname><given-names>Ұ. Ұ.</given-names></name><name name-style="western" xml:lang="en"><surname>Seitzhanova</surname><given-names>U. U.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сейтжанова Ұлдана Ұзақбайқызы, младший научный сотрудник, магистр ветеринарных наук</p></bio><email xlink:type="simple">uldan.2017@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1797-8350</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Есеналиева</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Yesenalieva</surname><given-names>A. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Есеналиева Асель Бахытжановна, старший лаборант</p></bio><email xlink:type="simple">asel_0888@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ТОО "Казахский научно исследовательский ветеринарный институт"<country>Казахстан</country></aff><aff xml:lang="en">LLP "Kazakh Scientific Research Veterinary Institute"<country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>14</day><month>10</month><year>2023</year></pub-date><volume>0</volume><issue>17</issue><fpage>46</fpage><lpage>56</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Борсынбаева А.М., Дюсенов С.М., Оразбеков Е.Б., Акжунусова И.К., Сейтжанова Ұ.Ұ., Есеналиева А.Б., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Борсынбаева А.М., Дюсенов С.М., Оразбеков Е.Б., Акжунусова И.К., Сейтжанова Ұ.Ұ., Есеналиева А.Б.</copyright-holder><copyright-holder xml:lang="en">Borsynbayeva A.M., Dyusenov S.M., Orazbekov E.B., Akzhunusova I.K., Seitzhanova U.U., Yesenalieva A.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.biosafety.kz/jour/article/view/123">https://journal.biosafety.kz/jour/article/view/123</self-uri><abstract><p>В статье приведены данные собственных исследований эпизоотической ситуации по туберкулезу в Карагандинской и Улытауской области за 2021-2024 годы. В 2024 году были выявлены два очага туберкулеза КРС в Карагандинской области, один из которых в Нуринском районе, сельский округ Ахметауылы, КХ «Кугабаев Н.» и другой в Бухар-Жырауском районе, сельский округ Кокпекты, ТОО «Джанат». Также были выявлены два очага туберкулеза КРС в Улытауской области, один из которых в Жана-аркинском районе, сельский округ М. Жумажанова, КХ «Диас» и один в городе Каражал - КХ «Пешковец». На основании ветеринарно-санитарного обследования туш и внутренних органов убитых животных был подтвержден диагноз туберкулез. Квалифицированное проведение аллергических исследований животными ветеринарными специалистами, а также дифференциальная диагностика неспецифических туберкулиновых реакций, позволяют точно определить эпизоотическую ситуацию по туберкулезу. Строгое соблюдение инструкций по диагностике и профилактике туберкулеза, наряду с выполнением разработанных ветеринарно-санитарных и организационно-хозяйственных мероприятий, способствует улучшению эпизоотической ситуации по туберкулезу. В конечном счете, это приводит к снижению риска заболеваемости туберкулезом среди людей</p></abstract><trans-abstract xml:lang="en"><p>The article presents data from our own research on the epizootic situation of tuberculosis in the Karaganda and Ulytau regions for 2021-2024. In 2024, two foci of cattle tuberculosis were identified in the Karaganda region, one of which in the Nurinsky district is the rural district of Akhmetauyly, KH "Kugabaev N." and the other in the Bukhar-Zhyrau district is the rural district of Kokpekty, LLP "Janat". Two foci of cattle tuberculosis were also identified in the Ulytau region, one of which is in the Zhana-Arkinsky district - the rural district of M. Zhumazhanov, KH "Dias" and one in the city of Karazhal - KH "Peshkovets". Based on a veterinary and sanitary examination of the carcasses and internal organs of the slaughtered animals, the diagnosis of tuberculosis was confirmed. The qualified conduct of allergic studies by animal veterinary specialists, as well as differential diagnosis of nonspecific tuberculin reactions, make it possible to accurately determine the epizootic situation of tuberculosis. Strict adherence to the instructions for the diagnosis and prevention of tuberculosis, along with the implementation of the developed veterinary and sanitary and organizational and economic measures, contributes to the improvement of the epizootic situation of tuberculosis. Ultimately, this leads to a reduction in the risk of tuberculosis among people</p></trans-abstract><kwd-group xml:lang="ru"><kwd>эпизоотология</kwd><kwd>мониторинг</kwd><kwd>туберкулез</kwd><kwd>диагностика</kwd><kwd>бактериология</kwd><kwd>микобактерии</kwd></kwd-group><kwd-group xml:lang="en"><kwd>еpizootology</kwd><kwd>monitoring</kwd><kwd>tuberculosis</kwd><kwd>diagnosis</kwd><kwd>bacteriology</kwd><kwd>mycobacteria</kwd></kwd-group><funding-group xml:lang="ru"><funding-statement>Работа финансировалась Министерством здравоохранения Республики Казахстан в рамках НТП ИРН BR218004/0223 «Совершенствование мер обеспечения биологической безопасности в Казахстане: противодействие опасным и особо опасным инфекциям» на 2023-2025 годы</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Smith, J., Economic impacts of bovine tuberculosis in livestock [Text] / J. Smith [and etc.] // Journal of Agricultural Economics – 2019. – Vol.71(3). P. 547-562.</mixed-citation><mixed-citation xml:lang="en">Smith, J., Economic impacts of bovine tuberculosis in livestock [Text] / J. Smith [and etc.] // Journal of Agricultural Economics – 2019. – Vol.71(3). P. 547-562.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Johnson, L., Control strategies for bovine tuberculosis: A global review [Text] / L. Johnson [and etc.] // Veterinary Science – 2020. – Vol.7(4). P. 105.</mixed-citation><mixed-citation xml:lang="en">Johnson, L., Control strategies for bovine tuberculosis: A global review [Text] / L. Johnson [and etc.] // Veterinary Science – 2020. – Vol.7(4). P. 105.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Brown, A., Veterinary approaches to managing bovine tuberculosis [Text] / A. Brown [and etc.] // Journal of Veterinary Medicine – 2018. – Vol.65(2). P. 213-229.</mixed-citation><mixed-citation xml:lang="en">Brown, A., Veterinary approaches to managing bovine tuberculosis [Text] / A. Brown [and etc.] // Journal of Veterinary Medicine – 2018. – Vol.65(2). P. 213-229.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Green, T., Diagnostic methods for bovine tuberculosis: Advances and challenges [Text] / T. Green // Veterinary Microbiology – 2021. P. 244.</mixed-citation><mixed-citation xml:lang="en">Green, T., Diagnostic methods for bovine tuberculosis: Advances and challenges [Text] / T. Green // Veterinary Microbiology – 2021. P. 244.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Lee, D., Bovine tuberculosis: Diagnosis and control. Infection Ecology &amp; Epidemiology [Text] / D. Lee [and etc.] // – 2017. Vol.7(1)</mixed-citation><mixed-citation xml:lang="en">Lee, D., Bovine tuberculosis: Diagnosis and control. Infection Ecology &amp; Epidemiology [Text] / D. Lee [and etc.] // – 2017. Vol.7(1)</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Taylor, G., Zoonotic tuberculosis: An emerging public health problem [Text] / G. Taylor [and etc.] // Infectious Diseases – 2016. Vol.48(7). P. 547-560.</mixed-citation><mixed-citation xml:lang="en">Taylor, G., Zoonotic tuberculosis: An emerging public health problem [Text] / G. Taylor [and etc.] // Infectious Diseases – 2016. Vol.48(7). P. 547-560.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Walker, H., Human and animal tuberculosis: A comprehensive review [Text] / H. Walker, J. Rodriguez // Global Health Research and Policy – 2018. Vol.3. P. 22.</mixed-citation><mixed-citation xml:lang="en">Walker, H., Human and animal tuberculosis: A comprehensive review [Text] / H. Walker, J. Rodriguez // Global Health Research and Policy – 2018. Vol.3. P. 22.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Martin, P., Strategies to eliminate bovine tuberculosis in high-incidence countries [Text] / P. Martin [and etc.] // Epidemiology and Infection – 2019. Vol.147. P.78.</mixed-citation><mixed-citation xml:lang="en">Martin, P., Strategies to eliminate bovine tuberculosis in high-incidence countries [Text] / P. Martin [and etc.] // Epidemiology and Infection – 2019. Vol.147. P.78.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Harris, B., Global efforts in combating bovine tuberculosis [Text] / B. Harris [and etc.] // Transboundary and Emerging Diseases – 2020. Vol.67(2). P. 623-635.</mixed-citation><mixed-citation xml:lang="en">Harris, B., Global efforts in combating bovine tuberculosis [Text] / B. Harris [and etc.] // Transboundary and Emerging Diseases – 2020. Vol.67(2). P. 623-635.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Williams, K., Vaccination strategies for bovine tuberculosis [Text] / K. Williams [and etc.] // Frontiers in Veterinary Science – 2022. Vol.9. P. 788573.</mixed-citation><mixed-citation xml:lang="en">Williams, K., Vaccination strategies for bovine tuberculosis [Text] / K. Williams [and etc.] // Frontiers in Veterinary Science – 2022. Vol.9. P. 788573.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Davis, R., New therapeutic approaches for bovine tuberculosis [Text] / R. Davis, M. Clark // Veterinary Research – 2019. Vol.50(1). P. 98.</mixed-citation><mixed-citation xml:lang="en">Davis, R., New therapeutic approaches for bovine tuberculosis [Text] / R. Davis, M. Clark // Veterinary Research – 2019. Vol.50(1). P. 98.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Джупина, С.И. Методы эпизоотологического исследования и теория эпизоотического процесса. [Текст] / С.И. Джупина // Новосибирск: СО «Наука». – 1991. – 139 с.</mixed-citation><mixed-citation xml:lang="en">Джупина, С.И. Методы эпизоотологического исследования и теория эпизоотического процесса. [Текст] / С.И. Джупина // Новосибирск: СО «Наука». – 1991. – 139 с.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Инструкция «О мероприятиях по профилактике и ликвидации туберкулеза животных». – Астана, 1999. – 29 с.</mixed-citation><mixed-citation xml:lang="en">Инструкция «О мероприятиях по профилактике и ликвидации туберкулеза животных». – Астана, 1999. – 29 с.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Turgenbayev, K.A., Tuberculosis prevalence in animals and humans in the Republic of Kazakhstan [Text] / K.A. Turgenbayev [and etc.] // Veterinary World. – 2021. – Vol.14(9). P. 2362-2370. doi: 10.14202/vetworld.2021.2362-2370. Epub 2021 Sep 11.</mixed-citation><mixed-citation xml:lang="en">Turgenbayev, K.A., Tuberculosis prevalence in animals and humans in the Republic of Kazakhstan [Text] / K.A. Turgenbayev [and etc.] // Veterinary World. – 2021. – Vol.14(9). P. 2362-2370. doi: 10.14202/vetworld.2021.2362-2370. Epub 2021 Sep 11.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
