biobБиобезопасность и БиотехнологияBiosafety and Biotechnology2707-72412957-5702Научно-исследовательский институт проблем биологической безопасности10.58318/2957-5702-2024-18-6-18biob-100Research ArticleСТАТЬИArticlesОСПА КОРОВ: КРАТКИЙ ОБЗОРCOWPOX: A BRIEF OVERVIEWhttps://orcid.org/0000-0001-6565-082XТуысқановаМ. С.TuyskanovaM. S.

Туысқанова Мөлдір Сержанқызы, младший научный сотрудник лаборатории «Коллекция микроорганизмов»

m.serzhankyzy@biosafety.kzhttps://orcid.org/0000-0001-6034-6642МамбеталиевМ.MambetalievM.

Мамбеталиев Муратбай, главный научный сотрудник лаборатории «Коллекция микроорганизмов»

m.mambetalyev@biosafety.kzhttps://orcid.org/0000-0003-4238-5116ЖугунисовК. Д.ZhugunissovK. D.

Жугунисов Куандык Даулетбаевич, PhD, заведующий лабораторией «Коллекция микроорганизмов»

k.Zhugunisov@biosafety.kz«Научно-исследовательский институт проблем биологической безопасности» МЗ РККазахстан«Research Institute for Biological Safety Problems» of the Ministry of Health of the RKKazakhstan202415102023018618Copyright © Туысқанова М.С., Мамбеталиев М., Жугунисов К.Д., 20232023Туысқанова М.С., Мамбеталиев М., Жугунисов К.Д.Tuyskanova M.S., Mambetaliev M., Zhugunissov K.D.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.biosafety.kz/jour/article/view/100

Оспа коров – заболевание, которое характеризуется быстрым развитием и рядом характерных симптомов. Болезнь характеризуется значительным повышением температуры тела, вызывая общую слабость и потерю аппетита. Это в свою очередь сказывается на молочной продуктивности. На вымени коровы появляются папулы, которые со временем превращаются в гнойники и трещины. За счет дискомфорта и болезненных ощущений у коровы появляется широкая стойка. Геном CPXV имеет самый полный набор генов среди всех ортопоксвирусов. Эта уникальная особенность CPXV делает его идеальным для мутирования в различные штаммы вируса. Это вирус с двуцепочечной ДНК. У вируса есть оболочка, которая окружает вирион. Анализированы литературные исследования, предоставляющие полезную информацию о клинических проявлениях чувствительности к данному вирусу для различных видов животных и людей. Изучение жизненного цикла этого вируса также является важным аспектом, поскольку раскрытие его механизмов позволяет разработать эффективные стратегии борьбы и контроля. Приведены конкретные примеры клинических проявлений, связанных с чувствительностью к данному вирусу у разных видов животных и людей. Это позволяет более полно оценить его потенциальные последствия и влияние на общественное здоровье

Cowpox is a disease characterized by rapid development and a number of characteristic symptoms. The disease is characterized by a significant increase in body temperature, causing general weakness and loss of appetite. This in turn affects milk production. Papules appear on the cow's udder, which over time turn into abscesses and cracks. Due to discomfort and pain, the cow develops a wide stance. The CPXV genome has the most complete gene set of any orthopoxvirus. This unique feature of CPXV makes it ideal for mutating into different strains of the virus. This is a double-stranded DNA virus. The virus has an envelope that surrounds the virion. Literature studies that provide useful information on the clinical manifestations of sensitivity to this virus for various animal species and humans are analyzed. Studying the life cycle of this virus is also an important aspect, since uncovering its mechanisms allows for the development of effective control and control strategies. Specific examples of clinical manifestations associated with sensitivity to this virus in different animal species and humans are given. This allows for a more complete assessment of its potential consequences and impact on public health

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The authors declare that there are no conflicts of interest present.